SCHEMBL112620

SCHEMBL112620

CC(C)(OC(N)=O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 3/20 0.37
EPHX1 P07099 1/20 0.37
NPC1 O15118 1/20 0.37
TSHR P16473 1/20 0.36
ALOX15 P16050 1/20 0.36
CYP17A1 P05093 2/20 0.36
CYP19A1 P11511 2/20 0.36
EPHX2 P34913 2/20 0.36
LMNA P02545 1/20 0.33
CRHBP P24387 1/20 0.33
HTT P42858 1/20 0.33
CRHR2 Q13324 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
GLA P06280 1/20 0.33
THRB P10828 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3290691 0.82 MEN1 (0.39) MEN1MAPK1KMT2AALDH1A1EPHX1
SCHEMBL441785 0.82 MEN1 (0.39) MEN1MAPK1KMT2AEPHX1ALOX15
SCHEMBL13638396 0.81 MEN1 (0.38) MEN1MAPK1KMT2AALDH1A1EPHX1
SCHEMBL14838346 0.81 MEN1 (0.38) MEN1MAPK1KMT2AALDH1A1EPHX1
SCHEMBL4903544 0.81 EPHX2 (0.39) MEN1MAPK1KMT2AALDH1A1ALOX15
SCHEMBL13527866 0.81 MEN1 (0.38) MEN1MAPK1KMT2AALDH1A1EPHX1
SCHEMBL19075500 0.79 CYP17A1 (0.38) MEN1MAPK1KMT2AEPHX1NPC1
SCHEMBL25968927 0.79 EPHX2 (0.43) MEN1MAPK1KMT2AALDH1A1CYP17A1
SCHEMBL17049827 0.79 KMT2A (0.41) MEN1MAPK1KMT2AALDH1A1EPHX1
SCHEMBL9608676 0.78 MEN1 (0.36) MEN1MAPK1KMT2AALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3729 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
EP-3715346-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2024-01-03 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
EP-3092220-B1 VITAMIN C PRODRUGS AND USES THEREOF UNIV FLORIDA (US) 2021-01-20 EP claimed
US-10870651-B2 Inhibitors of cyclin-dependent kinase 7 (CDK7) DANA-FARBER CANCER INSTITUTE, INC. (US) 2020-12-22 US claimed
EP-3171874-B1 IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2020-11-18 EP claimed
US-10711036-B2 MALT1 inhibitors and uses thereof CORNELL UNIVERSITY (US) 2020-07-14 US claimed
EP-2016044-B1 PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS HARVARD COLLEGE (US) 2020-06-10 EP claimed
EP-3209648-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2020-03-11 EP claimed
US-10112957-B2 Thiazolyl-containing compounds for treating proliferative diseases DANA-FARBER CANCER INSTITUTE, INC. (US) 2018-10-30 US claimed
US-9856225-B2 Substituted phenazines as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-01-02 US claimed
EP-2550285-B1 TRIOXACARCINS AND USES THEREOF HARVARD COLLEGE (US) 2017-07-19 EP claimed
US-20150376201-A1 CORTISTATIN ANALOGUES AND SYNTHESES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-12-31 US claimed
US-20130304089-A1 PERYLENEQUINONE DERIVATIVES AND USES THEREOF QUEST PHARMATECH INC. (CA) 2013-11-14 US claimed
US-5264583-A Photographic coupler and method of making the same EASTMAN KODAK COMPANY (US) 1993-11-23 US claimed
US-12637463-B2 Tricyclic kinase inhibitors and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-05-26 US disclosed
EP-0181061-A1 Labelling organic molecules with sulphur-35 AMERSHAM INTERNATIONAL plc (GB) 1986-05-14 EP disclosed