Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441785 | 0.84 | MEN1 (0.39) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL13527866 | 0.82 | MEN1 (0.38) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL14838346 | 0.82 | MEN1 (0.38) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL4903544 | 0.82 | EPHX2 (0.39) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL112620 | 0.82 | MEN1 (0.38) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL13638396 | 0.82 | MEN1 (0.38) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL4547708 | 0.82 | EPHX2 (0.39) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL17049827 | 0.81 | KMT2A (0.41) | MEN1MAPK1KMT2AEPHX2GLA | |
| SCHEMBL19075500 | 0.81 | CYP17A1 (0.38) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL25968927 | 0.81 | EPHX2 (0.43) | MEN1MAPK1KMT2AEPHX2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | claimed |
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | disclosed |
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |
| US-6759509-B1 | CONJUGATES CONTAINING A TARGETING LIGAND, SUCH AS AN ANTIBODY, A THERAPEUTICALLY ACTIVE DRUG AND A BRANCHED PEPTIDE LINKER | BRISTOL-MYERS SQUIBB COMPANY | 2004-07-06 | — | — | US | disclosed |