Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271370 | 0.94 | HMOX1 (0.44) | HMOX1NOS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11270747 | 0.92 | QPCT (0.41) | HMOX1CYP19A1PRKCIKDM4ELMNA | |
| SCHEMBL11262883 | 0.91 | QPCT (0.42) | HMOX1CYP19A1CYP11B1CYP11B2PRKCI | |
| SCHEMBL11257172 | 0.90 | CYP19A1 (0.40) | HMOX1CYP19A1PRKCI | |
| SCHEMBL11267577 | 0.90 | CYP2A6 (0.41) | HMOX1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11250043 | 0.90 | CYP19A1 (0.39) | CYP19A1CYP11B1CYP11B2PRKCIKDM4E | |
| SCHEMBL11257562 | 0.89 | HMOX1 (0.50) | HMOX1NOS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11255293 | 0.88 | MEN1 (0.47) | CYP19A1KDM4ELMNA | |
| SCHEMBL11255306 | 0.88 | HMOX1 (0.44) | HMOX1CYP19A1CYP11B1CYP11B2MAPK1 | |
| SCHEMBL11258691 | 0.87 | NOS1 (0.44) | HMOX1NOS1CYP19A1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |