SCHEMBL11262092

SCHEMBL11262092

CCC1CSC(CCc2ccc(Br)cc2)(CCn2ccnc2)S1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HMOX1 P09601 3/20 0.48
CYP19A1 P11511 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
MAPK1 P28482 1/20 0.40
NOS1 P29475 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11258240 0.92 QPCT (0.38) HMOX1CYP19A1
SCHEMBL11267271 0.91 CYP19A1 (0.42) HMOX1CYP19A1CYP11B1CYP11B2
SCHEMBL11271370 0.91 HMOX1 (0.44) HMOX1CYP19A1CYP11B1CYP11B2MAPK1
SCHEMBL11260146 0.91 HMOX1 (0.53) HMOX1CYP19A1CYP11B1CYP11B2
SCHEMBL11252554 0.90 HMOX1 (0.47) HMOX1
SCHEMBL11294735 0.90 HMOX1 (0.41) HMOX1CYP19A1CYP11B1CYP11B2
SCHEMBL11264753 0.89 HMOX1 (0.51) HMOX1CYP19A1CYP11B1CYP11B2MAPK1
SCHEMBL11264057 0.87 HMOX1 (0.46) HMOX1CYP19A1NOS1
SCHEMBL11262062 0.85 HMOX1 (0.47) HMOX1CYP19A1CYP11B1CYP11B2MAPK1
SCHEMBL11263551 0.85 HMOX1 (0.48) HMOX1CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359475-A SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS SYNTEX (U.S.A.) INC. (US) 1982-11-16 US disclosed