Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275803 | 1.00 | TSHR (0.44) | TSHRALDH1A1LPAR3LPAR2TDP1 | |
| SCHEMBL11573624 | 1.00 | TSHR (0.44) | TSHRALDH1A1LPAR3LPAR2TDP1 | |
| SCHEMBL10967393 | 0.91 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL7787426 | 0.89 | TSHR (0.48) | TSHRALDH1A1LPAR3LPAR2TDP1 | |
| SCHEMBL7783969 | 0.89 | TSHR (0.48) | TSHRALDH1A1LPAR3LPAR2TDP1 | |
| SCHEMBL11199398 | 0.87 | TSHR (0.44) | TSHRALDH1A1LPAR3LPAR2TDP1 | |
| SCHEMBL23493367 | 0.86 | LPAR3 (0.43) | TSHRLPAR3LPAR2THRBMEN1 | |
| SCHEMBL6652565 | 0.84 | LPAR3 (0.41) | TSHRLPAR3LPAR2THRBMEN1 | |
| SCHEMBL9009701 | 0.84 | LPAR3 (0.41) | TSHRLPAR3LPAR2THRBMEN1 | |
| SCHEMBL4810661 | 0.84 | LPAR3 (0.41) | TSHRLPAR3LPAR2THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332612-A | N-METHYL-2-PYRROLIDONE AND A HALOALKYL SILANE | GAF CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| US-4111974-A | Process for the production of alkoxy-β-halogenoethylsilanes | CIBA-GEIGY CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4102670-A | Beta-halogenoethyl-silanes as plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4102668-A | β-Halogenoethyl-silanes as plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4098601-A | Beta-halogenoethyl-silanes as plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-3985780-A | β-Halogenoethyl-silanes as plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |