SCHEMBL7787426

SCHEMBL7787426

CCCCCCCCO[Si](CCCCl)(OCCCCCCCC)OCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 1/20 0.48
TDP1 Q9NUW8 1/20 0.40
LPAR3 Q9UBY5 5/20 0.36
LPAR2 Q9HBW0 4/20 0.36
LMNA P02545 1/20 0.36
FAAH O00519 2/20 0.35
THRB P10828 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
NR5A1 Q13285 1/20 0.33
MAPT P10636 1/20 0.33
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA9 Q16790 4/20 0.32
LPAR1 Q92633 2/20 0.32
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783969 1.00 TSHR (0.48) TSHRALDH1A1TDP1LPAR3LPAR2
SCHEMBL11199398 0.98 TSHR (0.44) TSHRALDH1A1TDP1LPAR3LPAR2
SCHEMBL1132445 0.91 TSHR (0.43) TSHRALDH1A1TDP1LMNA
SCHEMBL11573624 0.89 TSHR (0.44) TSHRALDH1A1TDP1LPAR3LPAR2
SCHEMBL11262350 0.89 TSHR (0.44) TSHRALDH1A1TDP1LPAR3LPAR2
SCHEMBL11275803 0.89 TSHR (0.44) TSHRALDH1A1TDP1LPAR3LPAR2
SCHEMBL320518 0.88 TSHR (0.48) TSHRALDH1A1TDP1LMNAFAAH
SCHEMBL4810661 0.87 LPAR3 (0.41) TSHRLPAR3LPAR2LMNATHRB
SCHEMBL9009725 0.87 LPAR3 (0.41) TSHRLPAR3LPAR2LMNATHRB
SCHEMBL9009701 0.87 LPAR3 (0.41) TSHRLPAR3LPAR2LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US claimed
WO-2026105442-A1 COATING FILM, ELECTRONIC DEVICE, MOBILE BODY, AND COATING LIQUID ハドラスホールディングス株式会社 2026-05-21 WO disclosed
EP-0789053-B1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 2001-10-24 EP disclosed
US-6284777-B1 BONE DISORDERS SMITHKLINE BEECHAM CORPORATION 2001-09-04 US disclosed
US-6277902-B1 RUBBER COMPOUNDS COMPRISING SOLUBLE RUBBER, HYDROPHOBIZED FILLER HAVING SPECIFIED METHANOL WETTABILITY, SUPPORTEDPOLYSULFIDIC-SILANE COMPOUNDS PREPARED BY REACTION OF HALOALKYLSILANES, ORGANIC HALOGEN COMPOUNDS AND POLYSULFIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-08-21 US disclosed
US-5852138-A Stabilizer mixtures and their use in polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1998-12-22 US disclosed
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US disclosed
US-5770754-A Method of preparing polysulphidic silyl ethers BAYER AKTIENGESELLSCHAFT (DE) 1998-06-23 US disclosed
EP-0789053-A1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 1997-08-13 EP disclosed
EP-0507178-A2 Stabilization of high temperature deformation resistant polycarbonate BAYER AG (DE) 1992-10-07 EP disclosed
EP-0242627-A2 An improved process for preparing ester containing organosilicon compounds Wacker Silicones Corporation (US) 1987-10-28 EP disclosed
US-4647683-A Preparing ester containing organosilicon compounds (SWC) STAUFFER-WACKER SILICONES CORPORATION (US) 1987-03-03 US disclosed
US-4375525-A Use of organic silicon compounds for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1983-03-01 US disclosed
US-4342681-A Use of organic silicon compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-08-03 US disclosed
EP-0019217-A1 Use of organic silicium compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for the stabilisation and brightening of polycarbonates free from phosphites and boric acid esters BAYER AG (DE) 1980-11-26 EP disclosed