Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.58 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976720 | 0.82 | CNR2 (0.50) | CNR2PSEN1PSEN2APH1BNCSTN | |
| Benzene SCHEMBL28478449 | 0.81 | CNR2 (0.62) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL279246 | 0.81 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL9905344 | 0.79 | PSEN1 (0.62) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14107129 | 0.79 | PSEN1 (0.62) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL551644 | 0.79 | PSEN1 (0.62) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9976723 | 0.79 | PSEN1 (0.62) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6278388 | 0.79 | PGR (0.64) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6275417 | 0.79 | PGR (0.64) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL750975 | 0.79 | PGR (0.64) | CNR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014261-B1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3-(4-HYDROXYANILINO)-CARBAZOLE AND THE USE OF THE DERIVATIVES SO OBTAINED IN THE PREPARATION OF SULFUR DYES | CASSELLA Aktiengesellschaft (DE) | 1982-07-07 | — | — | EP | disclosed |