Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 11/20 | 0.62 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.62 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.62 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.62 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.62 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.62 |
| ▸ | CNR2 | P34972 | 8/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | RORA | P35398 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.57 |
| ▸ | RORB | Q92753 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976723 | 1.00 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14107129 | 1.00 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9905344 | 1.00 | PSEN1 (0.62) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL554428 | 0.98 | CNR2 (0.63) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6275417 | 0.93 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6278388 | 0.93 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1001993 | 0.93 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL750975 | 0.93 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1000878 | 0.93 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6575875 | 0.93 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512131-B2 | Organic semiconductor material for organic transistor, and organic transistor element | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20160049594-A1 | ORGANIC SEMICONDUCTOR MATERIAL FOR ORGANIC TRANSISTOR, AND ORGANIC TRANSISTOR ELEMENT | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
| US-20140088313-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2014-03-27 | — | — | US | disclosed |
| US-20140088313-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2014-03-27 | — | — | US | disclosed |
| US-8609867-B2 | Substituted indolocarbazoles | XEROX CORPORATION (US) | 2013-12-17 | — | — | US | disclosed |
| EP-1671998-B1 | Process to form compound with indolocarbazole moieties | XEROX CORP (US) | 2013-02-20 | — | — | EP | disclosed |
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-8110690-B2 | Substituted indolocarbazoles | XEROX CORPORATION (US) | 2012-02-07 | — | — | US | disclosed |
| US-8110690-B2 | Substituted indolocarbazoles | XEROX CORPORATION (US) | 2012-02-07 | — | — | US | disclosed |
| US-7402681-B2 | Compound with indolocarbazole moieties and devices containing such compound | XEROX CORPORATION (US) | 2008-07-22 | — | — | US | disclosed |
| US-7173140-B2 | Process to form compound with indolocarbazole moieties | XEROX CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173140-B2 | Process to form compound with indolocarbazole moieties | XEROX CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20060214155-A1 | Compound with indolocarbazole moieties and devices containing such compound | XEROX CORPORATION | 2006-09-28 | — | — | US | disclosed |
| EP-1672713-A1 | Compound with indolocarbazole moieties and electronic devices containing such compound | Xerox Corporation (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1671998-A2 | Process to form compound with indolocarbazole moieties | Xerox Corporation (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20060124923-A1 | Thin film transistors including indolocarbazoles | XEROX CORPORATION | 2006-06-15 | — | — | US | disclosed |
| US-20060124921-A1 | Compound with indolocarbazole moieties and devices containing such compound | XEROX CORPORATION (US) | 2006-06-15 | — | — | US | disclosed |
| US-20060125009-A1 | Thin film transistors including indolocarbazoles | XEROX CORPORATION | 2006-06-15 | — | — | US | disclosed |
| US-20060128969-A1 | Process to form compound with indolocarbazole moieties | XEROX CORPORATION | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160049594-A1 | ORGANIC SEMICONDUCTOR MATERIAL FOR ORGANIC TRANSISTOR, AND ORGANIC TRANSISTOR ELEMENT | SLC43A1, ALKBH3, TPR | PSEN1 2974/4885PSEN2 2210/4885APH1B 1130/4885 |
| US-20060128969-A1 | Process to form compound with indolocarbazole moieties | INMT, CYP3A4, PLK1 | PSEN1 2562/4885PSEN2 1935/4885APH1B 2711/4885 |
| US-20060214155-A1 | Compound with indolocarbazole moieties and devices containing such compound | BRD4, INO80C, BICRA | PSEN1 3929/4885PSEN2 2390/4885APH1B 2742/4885 |
| US-20060124921-A1 | Compound with indolocarbazole moieties and devices containing such compound | BRD4, INO80C, BICRA | PSEN1 3929/4885PSEN2 2390/4885APH1B 2742/4885 |
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | PSEN1 3162/4885PSEN2 1766/4885APH1B 4134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.