Methane

Methane

SCHEMBL11262863

C.O=C(O)Cc1cccc(C(=O)c2ccccc2)c1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
AKR1B1 P15121 1/20 0.57
ALDH1A1 P00352 1/20 0.52
PBRM1 Q86U86 1/20 0.52
SRD5A2 P31213 3/20 0.51
CYP19A1 P11511 1/20 0.50
VNN1 O95497 1/20 0.47
FOLH1 Q04609 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL11257402 0.98 ATM (0.59) ATMTDP1L3MBTL1AKR1B1ALDH1A1
SCHEMBL512838 0.98 ATM (0.63) ATMTDP1L3MBTL1AKR1B1ALDH1A1
Hydrochloric Acid SCHEMBL11844165 0.96 ATM (0.61) ATMTDP1L3MBTL1AKR1B1ALDH1A1
SCHEMBL19202273 0.94 AKR1B1 (0.58) ATMTDP1L3MBTL1AKR1B1PBRM1
SCHEMBL19202271 0.89 AKR1B1 (0.52) ATMTDP1L3MBTL1AKR1B1PBRM1
SCHEMBL9427627 0.88 CYP19A1 (0.53) ATMTDP1L3MBTL1AKR1B1SRD5A2
SCHEMBL15717569 0.86 SRD5A2 (0.59) ATMTDP1L3MBTL1AKR1B1SRD5A2
SCHEMBL11445035 0.86 L3MBTL1 (0.51) ATMTDP1L3MBTL1AKR1B1SRD5A2
Benzophenone SCHEMBL8820654 0.86 AKR1B1 (0.77) ATMTDP1L3MBTL1AKR1B1ALDH1A1
Methane SCHEMBL11255933 0.86 ATM (0.57) ATMTDP1L3MBTL1ALDH1A1PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116322662-A Compositions and methods for treating or preventing diseases associated with beta coronavirus infection 森贾姆制药有限责任公司 2023-06-23 CN disclosed
US-4362738-A ANTIINFLAMMATORIES DR. KARL THOMAE GMBH (DE) 1982-12-07 US disclosed