SCHEMBL19202271

SCHEMBL19202271

O=C(O)Cc1cccc(C(=O)c2cc(CC(=O)O)cc(CC(=O)O)c2)c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.52
TDP1 Q9NUW8 2/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
VNN1 O95497 1/20 0.47
FOLH1 Q04609 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
AGBL2 Q5U5Z8 1/20 0.45
SELP P16109 1/20 0.44
SELE P16581 1/20 0.44
HPSE Q9Y251 1/20 0.44
KDM4E B2RXH2 1/20 0.44
RGS12 O14924 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19202273 0.94 AKR1B1 (0.58) AKR1B1TDP1ATML3MBTL1VNN1
SCHEMBL512838 0.91 ATM (0.63) AKR1B1TDP1ATML3MBTL1VNN1
Hydrochloric Acid SCHEMBL11844165 0.89 ATM (0.61) AKR1B1TDP1ATML3MBTL1VNN1
Methane SCHEMBL11262863 0.89 ATM (0.61) AKR1B1TDP1ATML3MBTL1VNN1
SCHEMBL19202270 0.89 ALDH1A1 (0.56) AKR1B1TDP1ATML3MBTL1LMNA
Methane SCHEMBL11257402 0.87 ATM (0.59) AKR1B1TDP1ATML3MBTL1VNN1
SCHEMBL19202480 0.86 AKR1B1 (0.48) AKR1B1TDP1KDM4ERGS12LMNA
SCHEMBL9427627 0.84 CYP19A1 (0.53) AKR1B1TDP1ATML3MBTL1LMNA
SCHEMBL70565 0.84 AKR1B1 (0.71) AKR1B1TDP1CYP1A2CYP2C19SELP
SCHEMBL15717569 0.83 SRD5A2 (0.59) AKR1B1TDP1ATML3MBTL1VNN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548984-B2 Light- or heat-curing method and curable resin composition FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2023-01-10 US disclosed
US-10774062-B2 Photocuring method, compound and composition used therein FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-09-15 US disclosed
EP-3409709-B1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2020-08-19 EP disclosed
US-20200123324-A1 LIGHT- OR HEAT-CURING METHOD AND CURABLE RESIN COMPOSITION FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-04-23 US disclosed
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-02-21 US disclosed
WO-2017131047-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN 和光純薬工業株式会社 2017-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN ESD, TMT1A, PAM AKR1B1 1305/4885TDP1 3811/4885ATM 780/4885
US-10774062-B2 Photocuring method, compound and composition used therein ESD, TMT1A, PAM AKR1B1 1305/4885TDP1 3811/4885ATM 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.