Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27576716 | 0.85 | FSCN1 (0.36) | — | |
| SCHEMBL10441674 | 0.82 | HDAC3 (0.40) | TSHREPHX1EPHX2HDAC3HDAC1 | |
| SCHEMBL7983114 | 0.82 | TSHR (0.42) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11810698 | 0.80 | TSHR (0.41) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL19260913 | 0.80 | GAA (0.42) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11257421 | 0.79 | APEX1 (0.45) | TSHREPHX1EPHX2HDAC3HDAC1 | |
| SCHEMBL17060479 | 0.79 | HTR3E (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL526256 | 0.78 | TSHR (0.39) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11398672 | 0.78 | APEX1 (0.43) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15384804 | 0.78 | HDAC3 (0.38) | TSHREPHX1EPHX2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358611-A | FROM A PHENYLHYDRAZINE, A CHLOROFORMATE, PHOSGENE AND A SECONDARY AMINE | SHELL OIL COMPANY (US) | 1982-11-09 | — | — | US | disclosed |