Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29504742 | 0.93 | NPC1 (0.42) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL337227 | 0.93 | NPC1 (0.42) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4353102 | 0.87 | HSD17B10 (0.41) | TSHRHSD17B10CYP3A4ALDH1A1IDO1 | |
| SCHEMBL11851274 | 0.82 | F13A1 (0.43) | HDAC3HDAC1HDAC2HDAC6CYP3A4 | |
| SCHEMBL11810698 | 0.82 | TSHR (0.41) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11262864 | 0.82 | TSHR (0.41) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1879907 | 0.81 | ALDH1A1 (0.42) | TSHREPHX1EPHX2HSD17B10CYP3A4 | |
| SCHEMBL526256 | 0.80 | TSHR (0.39) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11398672 | 0.80 | APEX1 (0.43) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1304561 | 0.78 | PPARA (0.52) | TSHRCYP3A4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863852-A | A kind of addition method of new diuron | 安徽广信农化股份有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-104496855-B | Method for preparing diuron | 山东润博生物科技有限公司 | 2017-02-22 | — | — | CN | disclosed |
| WO-2015095202-A2 | ACTIVATORS OF MYOSIN II FOR MODULATING CELL MECHANICS | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-06-25 | — | — | WO | disclosed |
| CN-104496855-A | Method for preparing diuron | SHANDONG RUNBO BIOTECHNOLOGY CO LTD | 2015-04-08 | — | — | CN | disclosed |
| WO-2013155047-A2 | COMPOUNDS AND METHODS FOR INHIBITING CIF VIRULENCE FACTOR | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2013-10-17 | — | — | WO | disclosed |
| WO-2012103523-A2 | NOVEL MODULATORS OF DEVELOPMENT OF ADIPOCYTE AND CANCER CELLS | RAHBAR SAMUEL (US) | 2012-08-02 | — | — | WO | disclosed |
| US-6281240-B1 | CYSTIC FIBROSIS | ELI LILLY AND COMPANY | 2001-08-28 | — | — | US | disclosed |
| WO-1998044799-A1 | DIARYLSULFONYLUREAS FOR USE IN TREATING SECRETORY DIARRHEA | ELI LILLY AND COMPANY (US) | 1998-10-15 | — | — | WO | disclosed |
| EP-0555036-B1 | Antitumor compositions and methods of treatment | LILLY CO ELI (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0583960-B1 | Synthesis of bicyclic aromatic sulfonic acids, sulfonyl chlorides and sulfonamides | LILLY CO ELI (US) | 1997-05-21 | — | — | EP | disclosed |
| EP-0606723-A1 | Imidazolidin-2-one derivatives and their use as antitumor agents | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |
| EP-0583960-A2 | Synthesis of bicyclic aromatic sulfonic acids, sulfonyl chlorides and sulfonamides | ELI LILLY AND COMPANY (US) | 1994-02-23 | — | — | EP | disclosed |
| US-5270329-A | 1-arylsulfonyl-imidazolidin-2-one derivatives | ELI LILLY AND COMPANY (US) | 1993-12-14 | — | — | US | disclosed |
| US-5254582-A | Using n-((3,4-dichlorophenyl)amino)carbonyl)-2,3-dihydro-benzofuran-5-sulfonamide | ELI LILLY AND COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0555036-A2 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-08-11 | — | — | EP | disclosed |