Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049578 | 0.90 | RAB9A (0.45) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11052394 | 0.88 | NPC1 (0.40) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11054286 | 0.87 | HTT (0.43) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11254493 | 0.85 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11054793 | 0.84 | NPC1 (0.44) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11052848 | 0.82 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11053938 | 0.82 | HTT (0.47) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11579576 | 0.82 | RAB9A (0.50) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11049778 | 0.82 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11052869 | 0.81 | HTT (0.43) | ALDH1A1RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |