Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270301 | 0.78 | NPY5R (0.48) | CTSSCTSKLMNASMN1; SMN2NPY5R | |
| SCHEMBL4384695 | 0.75 | EPHX2 (0.49) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11155028 | 0.73 | MAPT (0.47) | LMNASMN1; SMN2KDM4EAPPNPC1 | |
| SCHEMBL20402847 | 0.72 | ACP1 (0.61) | CTSSCTSKSMN1; SMN2NPY5RKDM4E | |
| SCHEMBL20938766 | 0.72 | ACP1 (0.61) | CTSSCTSKSMN1; SMN2NPY5RKDM4E | |
| SCHEMBL11265077 | 0.72 | KCNH3 (0.57) | LMNAKDM4EGAA | |
| SCHEMBL18557173 | 0.72 | ACP1 (0.61) | CTSSCTSKSMN1; SMN2NPY5RKDM4E | |
| SCHEMBL8050442 | 0.72 | ACP1 (0.61) | CTSSCTSKSMN1; SMN2NPY5RKDM4E | |
| SCHEMBL3296576 | 0.72 | PDE4A (0.64) | CTSSCTSKHTTSMN1; SMN2NPY5R | |
| SCHEMBL11252354 | 0.71 | APP (0.47) | LMNACYP1A2HTTGAAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339577-A | CROSSLINKING INHIBITORS FOR RUBBERS | MONSANTO COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4301260-A | Vulcanizable rubber compositions scorch inhibited by 2-(thioamino)-4,6-diamino-1,3,5-triazines | MONSANTO COMPANY (US) | 1981-11-17 | — | — | US | disclosed |