Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155028 | 0.81 | MAPT (0.47) | KCNH3MEN1MAPTKMT2AMAPK1 | |
| SCHEMBL11252354 | 0.78 | APP (0.47) | KCNH3MEN1KMT2AGAAMAPK1 | |
| SCHEMBL3431056 | 0.77 | IDO1 (0.40) | METAP2METAP1LMNA | |
| SCHEMBL11254673 | 0.77 | NPSR1 (0.46) | MEN1MAPTKMT2ANPSR1LMNA | |
| SCHEMBL633400 | 0.77 | MEN1 (0.77) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL11256328 | 0.73 | ALDH1A1 (0.51) | MEN1MAPTKMT2AMAPK1NPSR1 | |
| SCHEMBL11257385 | 0.73 | MEN1 (0.55) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL18123046 | 0.72 | MEN1 (0.71) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL11263145 | 0.72 | CTSS (0.51) | GAAKDM4ELMNA | |
| SCHEMBL8506448 | 0.71 | MEN1 (0.63) | KCNH3MEN1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339577-A | CROSSLINKING INHIBITORS FOR RUBBERS | MONSANTO COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4301260-A | Vulcanizable rubber compositions scorch inhibited by 2-(thioamino)-4,6-diamino-1,3,5-triazines | MONSANTO COMPANY (US) | 1981-11-17 | — | — | US | disclosed |