Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TFEB | P19484 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263148 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL31312540 | 0.86 | NFE2L2 (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL3536949 | 0.85 | SMN1; SMN2 (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL15188 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL3536947 | 0.85 | SMN1; SMN2 (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL31506312 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL13957562 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL4775241 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL10783189 | 0.84 | CA12 (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| SCHEMBL23591532 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1HPGDNFE2L2TFEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |