Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 3/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | METAP2 | P50579 | 2/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | COMT | P21964 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cloxyquin SCHEMBL28072521 | 0.92 | KDM4E (0.68) | KDM4EL3MBTL1HSP90AA1LMNAHTT | |
| SCHEMBL6624088 | 0.75 | IDO1 (0.52) | KDM4EMAPTIDO1GAAALDH1A1 | |
| SCHEMBL1187421 | 0.75 | HSP90AA1 (0.61) | KDM4EL3MBTL1HSP90AA1LMNAHTT | |
| SCHEMBL1920452 | 0.74 | KDM4E (0.70) | KDM4EL3MBTL1HSP90AA1LMNAHTT | |
| SCHEMBL4301084 | 0.73 | HSP90AA1 (0.59) | KDM4EL3MBTL1HSP90AA1LMNAHTT | |
| SCHEMBL22604619 | 0.73 | KDM4E (0.58) | KDM4EL3MBTL1HSP90AA1LMNAHTT | |
| SCHEMBL27816447 | 0.73 | KDM4E (0.68) | KDM4EL3MBTL1HSP90AA1LMNAHTT | |
| Methane SCHEMBL27551425 | 0.73 | KDM4E (0.68) | KDM4EL3MBTL1HSP90AA1LMNAHTT | |
| SCHEMBL7694506 | 0.72 | KDM4E (0.61) | KDM4EL3MBTL1HSP90AA1LMNAHTT | |
| SCHEMBL145244 | 0.72 | KDM4E (0.61) | KDM4EL3MBTL1HSP90AA1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10729630-B2 | Shaping keratin fibres using an active agent comprising at least two functional groups selected from: —C(OH)- and —C(=O)OH | THE PROCTER & GAMBLE COMPANY (US) | 2020-08-04 | — | — | US | claimed |
| CN-105828786-B | Shaping keratin fibres using AN AN active agent comprising a functional group selected from-C (═ O) -, -C (═ O) -H and-C (═ O) -O-) | 宝洁公司 | 2020-07-07 | — | — | CN | claimed |
| CN-105828793-B | Shaping keratin fibres using sugar | 宝洁公司 | 2019-06-18 | — | — | CN | claimed |
| EP-3082494-B1 | METHOD FOR SHAPING FIBROUS MATERIAL | PROCTER & GAMBLE (US) | 2018-12-05 | — | — | EP | claimed |
| EP-3082746-B1 | SHAPING KERATIN FIBRES USING AN AMINE OR A DIAMINE | PROCTER & GAMBLE (US) | 2018-11-28 | — | — | EP | claimed |
| EP-3082736-B1 | SHAPING KERATIN FIBRES USING 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID AND/OR 1,2,3,4-BUTANETETRACARBOXYLIC ACID | PROCTER & GAMBLE (US) | 2018-08-08 | — | — | EP | claimed |
| EP-3082747-B1 | SHAPING KERATIN FIBRES USING A SUGAR | PROCTER & GAMBLE (US) | 2018-07-04 | — | — | EP | claimed |
| EP-3082731-B1 | SHAPING KERATIN FIBRES USING AN ACTIVE AGENT COMPRISING AT LEAST TWO FUNCTIONAL GROUPS SELECTED FROM: -C(OH)- AND -C(=O)OH | PROCTER & GAMBLE (US) | 2018-07-04 | — | — | EP | claimed |
| EP-3082735-B1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | PROCTER & GAMBLE (US) | 2018-05-02 | — | — | EP | claimed |
| US-9918921-B2 | Methods for shaping fibrous material and treatment compositions therefor | THE PROCTER & GAMBLE COMPANY (US) | 2018-03-20 | — | — | US | claimed |
| WO-2015094757-A1 | SHAPING KERATIN FIBRES USING A SUGAR | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| WO-2015094787-A1 | METHODS FOR SHAPING FIBROUS MATERIAL AND TREATMENT COMPOSITIONS THEREFOR | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| WO-2015094759-A1 | SHAPING KERATIN FIBRES USING AN ACTIVE AGENT COMPRISING AT LEAST TWO FUNCTIONAL GROUPS SELECTED FROM: -C(OH)- AND -C(=O)OH | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| WO-2015094788-A1 | METHODS FOR SHAPING FIBROUS MATERIAL AND TREATMENT COMPOSITIONS THEREFOR | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| WO-2015095671-A1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| WO-2015094784-A1 | METHODS FOR SHAPING FIBROUS MATERIAL AND TREATMENT COMPOSITIONS THEREFOR | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| US-20150173478-A1 | Methods for Shaping Fibrous Material and Treatment Compositions Therefor | THE PROCTER & GAMBLE COMPANY | 2015-06-25 | — | — | US | claimed |
| US-20150174029-A1 | SHAPING KERATIN FIBRES USING AN ACTIVE AGENT COMPRISING AT LEAST TWO FUNCTIONAL GROUPS SELECTED FROM: -C(OH)- AND -C(=O)OH | THE PROCTER & GAMBLE COMPANY | 2015-06-25 | — | — | US | claimed |
| WO-2015094756-A1 | SHAPING KERATIN FIBRES USING AN AMINE OR A DIAMINE | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| WO-2015094790-A1 | METHODS FOR SHAPING FIBROUS MATERIAL AND TREATMENT COMPOSITIONS THEREFOR | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174029-A1 | SHAPING KERATIN FIBRES USING AN ACTIVE AGENT COMPRISING AT LEAST TWO FUNCTIONAL GROUPS SELECTED FROM: -C(OH)- AND -C(=O)OH | KRT18, CKAP4, JUP | KDM4E 195/4885L3MBTL1 4733/4885HSP90AA1 1080/4885 |
| US-10729630-B2 | Shaping keratin fibres using an active agent comprising at least two functional groups selected from: —C(OH)- and —C(=O)OH | KRT18, CKAP4, JUP | KDM4E 181/4885L3MBTL1 4734/4885HSP90AA1 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.