SCHEMBL1920452

SCHEMBL1920452

Oc1ccc(O)c2ncccc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.70
L3MBTL1 Q9Y468 5/20 0.70
HSP90AA1 P07900 4/20 0.70
LMNA P02545 4/20 0.70
MAPT P10636 4/20 0.70
HTT P42858 3/20 0.70
IDO1 P14902 2/20 0.70
BRD4 O60885 2/20 0.70
METAP2 P50579 2/20 0.70
MPI P34949 1/20 0.70
METAP1 P53582 1/20 0.70
HSP90AB1 P08238 1/20 0.70
PSMB5 P28074 1/20 0.70
SLC6A2 P23975 1/20 0.70
NPC1 O15118 4/20 0.68
RAB9A P51151 4/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
GAA P10253 1/20 0.68
NPSR1 Q6W5P4 2/20 0.63
FTO Q9C0B1 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL27551425 0.98 KDM4E (0.68) KDM4EL3MBTL1HSP90AA1LMNAMAPT
SCHEMBL27816447 0.98 KDM4E (0.68) KDM4EL3MBTL1HSP90AA1LMNAMAPT
Methane SCHEMBL28088738 0.96 KDM4E (0.66) KDM4EL3MBTL1HSP90AA1LMNAMAPT
SCHEMBL31481274 0.86 KDM4E (0.74) KDM4EL3MBTL1HSP90AA1LMNAMAPT
SCHEMBL1333120 0.84 KDM4E (0.66) KDM4EL3MBTL1HSP90AA1LMNAMAPT
SCHEMBL30668494 0.84 KDM4E (0.66) KDM4EL3MBTL1HSP90AA1LMNAMAPT
SCHEMBL1133269 0.83 HSP90AA1 (0.72) KDM4EL3MBTL1HSP90AA1LMNAMAPT
Tiliquinol SCHEMBL145245 0.83 HTT (1.00) KDM4EL3MBTL1HSP90AA1LMNAMAPT
SCHEMBL7694506 0.83 KDM4E (0.61) KDM4EL3MBTL1HSP90AA1LMNAMAPT
SCHEMBL12599432 0.83 LMNA (0.53) KDM4EL3MBTL1HSP90AA1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0183567-B1 PROCESS FOR PRODUCING POLYPHENYLENE ETHERS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-03-29 EP claimed
US-4617372-A MANGANESE SALT, OXINE DERIVATIVES, ALKANOLAMINE AND ALKALINE COMPOUND AS CATALYST MITSUBISHI PETROCHEMICAL CO, LTD. (JP) 1986-10-14 US claimed
EP-0183567-A1 Process for producing polyphenylene ethers MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-06-04 EP claimed
US-20250041824-A1 CARBON DIOXIDE ADSORBENT AND CARBON DIOXIDE ADSORPTION-DESORPTION DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2025-02-06 US disclosed
EP-4501446-A1 CARBON DIOXIDE ADSORBENT AND CARBON DIOXIDE ADSORPTION-DESORPTION DEVICE Kabushiki Kaisha Toshiba (JP) 2025-02-05 EP disclosed
CN-117777433-A Polyphenylene ether, process for producing the same, and thermosetting resin 中化学科学技术研究有限公司 2024-03-29 CN disclosed
CN-114514470-A Pattern forming method, photosensitive resin composition, method for manufacturing laminate, and method for manufacturing semiconductor device 富士胶片株式会社 2022-05-17 CN disclosed
CN-113383273-A Photosensitive resin composition, pattern forming method, cured film, laminate, and device 富士胶片株式会社 2021-09-10 CN disclosed
CN-113168093-A Pattern forming method, photosensitive resin composition, cured film, laminate, and device 富士胶片株式会社 2021-07-23 CN disclosed
EP-3555052-A1 N-OXIDE HETEROCYCLES FOR USE IN THE TREATMENT OF CANCER AND BACTERIAL DISEASES Rongved, Pål (NO) 2019-10-23 EP disclosed
CN-106008322-B sulfonamide derivatives as BC L-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases ABBVIE 公司 2018-09-04 CN disclosed
US-4822719-A Radiation-sensitive mixture, radiation-sensitive recording material containing said mixture, and process for preparing relief images HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-18 US disclosed
EP-0183567-B1 PROCESS FOR PRODUCING POLYPHENYLENE ETHERS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-03-29 EP disclosed
US-4617372-A MANGANESE SALT, OXINE DERIVATIVES, ALKANOLAMINE AND ALKALINE COMPOUND AS CATALYST MITSUBISHI PETROCHEMICAL CO, LTD. (JP) 1986-10-14 US disclosed
EP-0183567-A1 Process for producing polyphenylene ethers MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-06-04 EP disclosed
US-4286045-A A SUPPORT HAVING A LAYER OF A CHALCOGENIDE OF GERMANIUM DOPED WITH SILVER OR COPPER; STABILITY; LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1981-08-25 US disclosed
US-4198237-A GERMANIUM SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-04-15 US disclosed
US-4197124-A SILVER OR COPPER AND SULFUR, SELENIUM OR TELLURIUM0 FUJI PHOTO FILM CO., LTD. (JP) 1980-04-08 US disclosed
US-4177072-A HYDROPHILIC AND OLEOPHILIC AREAS FUJI PHOTO FILM CO., LTD. (JP) 1979-12-04 US disclosed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041824-A1 CARBON DIOXIDE ADSORBENT AND CARBON DIOXIDE ADSORPTION-DESORPTION DEVICE SCO2, EPCAM, ENO1 KDM4E 523/4885L3MBTL1 1225/4885HSP90AA1 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.