Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272626 | 0.87 | ALDH1A1 (0.55) | MAPK1GAAHTTNPSR1MAPT | |
| SCHEMBL5073540 | 0.87 | CYP1A2 (0.69) | GAAHTTMAPTALDH1A1TDP1 | |
| SCHEMBL11575925 | 0.84 | CYP1A2 (0.68) | GAAHTTMAPTALDH1A1LMNA | |
| SCHEMBL11272622 | 0.84 | ALDH1A1 (0.51) | MAPK1GAAHTTNPSR1MAPT | |
| SCHEMBL16550142 | 0.83 | L3MBTL1 (0.71) | MAPK1GAAHTTMAPTALDH1A1 | |
| SCHEMBL29435299 | 0.81 | MAPT (0.67) | MAPK1GAAHTTNPSR1MAPT | |
| SCHEMBL512092 | 0.81 | MAPT (0.67) | MAPK1GAAHTTNPSR1MAPT | |
| SCHEMBL11272623 | 0.81 | TDP1 (0.54) | MAPK1NPSR1MAPTALDH1A1TDP1 | |
| SCHEMBL11095128 | 0.80 | ALDH1A1 (0.73) | MAPK1GAAHTTNPSR1MAPT | |
| SCHEMBL9365255 | 0.80 | CYP1A2 (0.67) | MAPK1GAAHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4323691-A | Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters | ABBOTT LABORATORIES (US) | 1982-04-06 | — | — | US | disclosed |