Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251707 | 0.80 | CTNNB1 (0.40) | HRH1HSD17B10LMNAALDH1A1MAPT | |
| SCHEMBL11183688 | 0.78 | HRH1 (0.39) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL11189445 | 0.77 | RAB9A (0.46) | HRH1LMNAALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9756590 | 0.75 | HRH1 (0.42) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL11253725 | 0.75 | MAOA (0.43) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL4612152 | 0.74 | HRH3 (0.46) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL28140567 | 0.74 | HRH3 (0.46) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL28319826 | 0.74 | HRH1 (0.48) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL9113864 | 0.72 | CSNK1A1 (0.43) | HSD17B10HRH3LMNAALDH1A1MAPT | |
| SCHEMBL12854110 | 0.72 | HRH3 (0.43) | HRH1HRH3LMNATAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327102-A | TREATING ULCERS AND HYPERSECRETION | JOHN WYETH & BROTHER LIMITED (GB) | 1982-04-27 | — | — | US | claimed |