Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfachlorpyridazine SCHEMBL38650642 | 0.82 | LMNA (1.00) | LMNAKDM4ENPSR1GAAPKM | |
| Sulfachlorpyridazine SCHEMBL94138 | 0.82 | LMNA (1.00) | LMNAKDM4ENPSR1GAAPKM | |
| Sulfachlorpyridazine SCHEMBL29468586 | 0.82 | LMNA (1.00) | LMNAKDM4ENPSR1GAAPKM | |
| SCHEMBL924615 | 0.82 | GAA (1.00) | LMNAKDM4ENPSR1GAAPOLB | |
| Sulfachlorpyridazine SCHEMBL203598 | 0.81 | LMNA (0.97) | LMNAKDM4ENPSR1GAAPKM | |
| Sulfachlorpyridazine SCHEMBL28539972 | 0.81 | LMNA (0.97) | LMNAKDM4ENPSR1GAAPKM | |
| SCHEMBL11265987 | 0.81 | LMNA (0.71) | LMNAPOLBPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL11882135 | 0.78 | POLB (0.55) | LMNAPOLBPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL24298640 | 0.77 | POLB (0.56) | LMNAPOLBPKMSMN1; SMN2ALDH1A1 | |
| Sulfachlorpyridazine SCHEMBL23420334 | 0.76 | LMNA (0.80) | LMNAKDM4ENPSR1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315931-A | MICROBIOCIDES, INFECTIOUS DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| US-4333936-A | Novel amidino-benzylpyrimidines, processes for their manufacture and antibacterial and antiprotozoal use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| US-4315931-A | MICROBIOCIDES, INFECTIOUS DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |