Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.52 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamethoxypyridazine SCHEMBL10777132 | 0.83 | LMNA (1.00) | LMNASMN1; SMN2CYP2C19ALDH1A1MAPT | |
| Sulfamethoxypyridazine SCHEMBL93617 | 0.83 | LMNA (1.00) | LMNASMN1; SMN2CYP2C19ALDH1A1MAPT | |
| Sulfamethoxypyridazine SCHEMBL29377020 | 0.83 | LMNA (1.00) | LMNASMN1; SMN2CYP2C19ALDH1A1MAPT | |
| Sulfamethoxypyridazine SCHEMBL29360723 | 0.83 | LMNA (1.00) | LMNASMN1; SMN2CYP2C19ALDH1A1MAPT | |
| Sulfamethoxypyridazine SCHEMBL11516439 | 0.82 | LMNA (0.97) | LMNASMN1; SMN2CYP2C19ALDH1A1MAPT | |
| Sulfamethoxypyridazine SCHEMBL27484423 | 0.82 | LMNA (0.97) | LMNASMN1; SMN2CYP2C19ALDH1A1MAPT | |
| SCHEMBL11263565 | 0.81 | LMNA (0.69) | LMNASMN1; SMN2CYP2C19ALDH1A1POLB | |
| Sulfamethoxypyridazine SCHEMBL11026411 | 0.81 | LMNA (0.94) | LMNASMN1; SMN2CYP2C19ALDH1A1MAPT | |
| SCHEMBL11882135 | 0.76 | POLB (0.55) | LMNASMN1; SMN2ALDH1A1PIK3C2BPIK3C2G | |
| SCHEMBL12325142 | 0.75 | F2 (0.58) | LMNASMN1; SMN2ALDH1A1PIK3C2BPIK3C2G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315931-A | MICROBIOCIDES, INFECTIOUS DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| US-4333936-A | Novel amidino-benzylpyrimidines, processes for their manufacture and antibacterial and antiprotozoal use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| US-4315931-A | MICROBIOCIDES, INFECTIOUS DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| EP-0000335-B1 | ESTERS OF N-PYRIMIDINYL-CARBOXIMIDIC ACID, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM. | BASF Aktiengesellschaft (DE) | 1981-10-07 | — | — | EP | disclosed |
| EP-0000334-B1 | 2,4-DIAMINO-5-BENZYL-PYRIMIDINES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-08-12 | — | — | EP | disclosed |
| US-4279899-A | MICROBIOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |
| EP-0000336-B1 | N-BENZYLPYRIMIDINYL-AMIDINES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |
| EP-0000334-A1 | 2,4-Diamino-5-benzyl-pyrimidines, process for their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1979-01-24 | — | — | EP | disclosed |
| EP-0000335-A1 | Esters of N-pyrimidinyl-carboximidic acid, process for their preparation and medicines containing them. | BASF Aktiengesellschaft (DE) | 1979-01-24 | — | — | EP | disclosed |
| EP-0000336-A1 | N-benzylpyrimidinyl-amidines, process for their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1979-01-24 | — | — | EP | disclosed |