Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2261746 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNACCNE2CDK4CCND1 | |
| SCHEMBL196611 | 0.78 | TDP1 (0.32) | ALDH1A1 | |
| SCHEMBL4425991 | 0.78 | KDM5A (0.33) | ALDH1A1 | |
| SCHEMBL16027083 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1444734 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNACCNE2CDK4CCND1 | |
| SCHEMBL27755264 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNACCNE2CDK4CCND1 | |
| SCHEMBL1977535 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNACCNE2CDK4CCND1 | |
| SCHEMBL16026843 | 0.73 | NOTUM (0.32) | — | |
| SCHEMBL147656 | 0.70 | — | — | |
| SCHEMBL4052124 | 0.70 | TRIM24 (0.40) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343648-A | 6H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-10 | — | — | US | disclosed |