SCHEMBL147656

SCHEMBL147656

O=CNc1cc[c]cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5941013 0.86 ALDH1A1 (0.48)
SCHEMBL469386 0.80 ALDH1A1 (0.72)
SCHEMBL27817562 0.77 ALDH1A1 (0.33)
SCHEMBL10906049 0.75 ALDH1A1 (0.31)
SCHEMBL23353504 0.72 ALDH1A1 (1.00)
Formanilide SCHEMBL2463 0.72
Formanilide SCHEMBL29177030 0.72 ALDH1A1 (1.00)
SCHEMBL11178145 0.72 ALDH1A1 (0.32)
SCHEMBL271314 0.72
Formanilide SCHEMBL11419741 0.70 ALDH1A1 (0.94)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 857 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023158722-A2 PROCESSES FOR PREPARATION OF AVACOPAN AND INTERMEDIATES THEREOF TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) 2023-08-24 WO claimed
CN-112457255-A Compounds and their use for treating cancer 北京嘉林药业股份有限公司 2021-03-09 CN claimed
US-20200354342-A1 2-(1H-PYRAZOL-3-YL) PHENOL COMPOUND AND USE THEREOF BEIJING JIALIN PHARMACEUTICAL INC. (CN) 2020-11-12 US claimed
EP-3705476-A1 2-(1H-PYRAZOL-3-YL) PHENOL COMPOUND AND USE THEREOF Beijing Jialin Pharmaceutical Inc. (CN) 2020-09-09 EP claimed
CN-211384996-U Formamido phenyl boric acid preparation reaction kettle device 武汉利昌医药科技有限公司 2020-09-01 CN claimed
US-20190284140-A1 COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS THE BROAD INSTITUTE, INC. 2019-09-19 US claimed
CN-109641930-A The preparation method of the fluoro- 2- methyl deoxyribonucleoside of 2- as Suo Feibuwei intermediate 正大天晴药业集团股份有限公司 2019-04-16 CN claimed
CN-106543131-B The PI3K/Akt signal pathway inhibitors S14161 and its preparation method and application of 18F labels 山东大学齐鲁医院 2018-07-24 CN claimed
CN-107805266-A Preparation method as the methyl deoxyribonucleoside of 2 fluorine 2 of Suo Feibuwei intermediates 上海度德医药科技有限公司 2018-03-16 CN claimed
WO-2017027768-A1 COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS THE BROAD INSTITUTE, INC. (US) 2017-02-16 WO claimed
EP-0184384-A1 Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them PFIZER INC. (US) 1986-06-11 EP claimed
US-4363808-A N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1982-12-14 US claimed
EP-0048159-A2 Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents UNIVERSITY OF MIAMI (US) 1982-03-24 EP claimed
EP-0034116-A2 N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1981-08-19 EP claimed
US-4272546-A ANTILIPEMIC, ANTIATHEROSCLEROTIC AMERICAN CYANAMID COMPANY (US) 1981-06-09 US claimed
US-4262851-A HIGH SPEED MILLING WITHOUT SURFACTANTS BASF AKTIENGESELLSCHAFT (DE) 1981-04-21 US claimed
EP-0003021-A1 Cyano-oligomer compositions and processes thereof GAF CORPORATION (US) 1979-07-25 EP claimed
US-4157396-A Hydroxamic acid derivatives and medicaments for treatment of urolithiasis and pyelonephrosis comprising such derivatives EISAI CO., LTD. (JP) 1979-06-05 US claimed
US-4128536-A ULTRAVIOLET LIGHT ABSORBERS GAF CORPORATION (US) 1978-12-05 US claimed
US-3988326-A Process for N-acylation of 7 amino cephem compounds MEIJI SEIKA KAISHA, LTD. (JA) 1976-10-26 US claimed