Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265824 | 0.91 | KMT2A (0.43) | KMT2AMEN1ATMQPCTALDH1A1 | |
| SCHEMBL11262210 | 0.90 | KMT2A (0.45) | KMT2AMEN1ATMQPCTALDH1A1 | |
| SCHEMBL11258196 | 0.89 | QPCT (0.40) | KMT2AMEN1QPCTALDH1A1TSHR | |
| SCHEMBL11273217 | 0.88 | QPCT (0.39) | QPCTALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL11262046 | 0.88 | TBXAS1 (0.39) | KMT2AMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL11262841 | 0.84 | MEN1 (0.46) | KMT2AMEN1ATMQPCTALDH1A1 | |
| SCHEMBL11262057 | 0.83 | MEN1 (0.43) | KMT2AMEN1ATMQPCTALDH1A1 | |
| SCHEMBL11257033 | 0.82 | KMT2A (0.43) | KMT2AMEN1ATMQPCTALDH1A1 | |
| SCHEMBL11264351 | 0.82 | CYP3A4 (0.43) | KMT2AMEN1ATMQPCTALDH1A1 | |
| SCHEMBL11266893 | 0.82 | MEN1 (0.46) | KMT2AMEN1ATMQPCTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |