Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258196 | 0.91 | QPCT (0.40) | TBXAS1CYP19A1CYP11B1CYP11B2MEN1 | |
| SCHEMBL11255809 | 0.90 | TBXAS1 (0.38) | TBXAS1CYP19A1OPRM1OPRL1CYP11B1 | |
| SCHEMBL11273217 | 0.90 | QPCT (0.39) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL11268382 | 0.89 | CYP19A1 (0.39) | TBXAS1CYP19A1OPRM1OPRL1CYP11B1 | |
| SCHEMBL11263602 | 0.88 | KMT2A (0.44) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11269340 | 0.82 | CYP19A1 (0.40) | TBXAS1CYP19A1OPRM1OPRL1CYP11B1 | |
| SCHEMBL11256558 | 0.82 | CYP1A2 (0.37) | TBXAS1CYP19A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL11251104 | 0.81 | CYP19A1 (0.38) | TBXAS1CYP19A1OPRM1OPRL1CYP11B1 | |
| SCHEMBL11272439 | 0.81 | HMOX1 (0.38) | TBXAS1CYP19A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL11254517 | 0.81 | QPCT (0.38) | TBXAS1CYP19A1CYP11B1CYP11B2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |