Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6066151 | 0.84 | ALDH1A1 (0.38) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL15715983 | 0.81 | GABRA1 (0.49) | MAPK1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL11252971 | 0.81 | CHEK1 (0.48) | MAPK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL11319704 | 0.81 | ALDH1A1 (0.42) | MAPK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL21632972 | 0.79 | MAPK1 (0.43) | MAPK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL15715957 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL11365421 | 0.78 | ALDH1A1 (0.44) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL11262688 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL17111627 | 0.77 | MAPK1 (0.45) | MAPK1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL11388630 | 0.77 | ALDH1A1 (0.43) | MAPK1MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363909-A | ANTIVIRAL AGENTS | RHONE POULENC INDUSTRIES (FR) | 1982-12-14 | — | — | US | disclosed |