Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.46 |
| ▸ | APLNR | P35414 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263318 | 0.81 | ALDH1A1 (0.44) | HTTMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL27767382 | 0.78 | HTT (0.76) | AGTR1HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL11275070 | 0.78 | HTT (0.71) | HTTMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL11276109 | 0.78 | HTT (0.71) | AGTR1HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL12814738 | 0.75 | NPC1 (0.71) | MAPTSMN1; SMN2LMNAKMT2ARAB9A | |
| SCHEMBL11273547 | 0.75 | HTT (0.51) | HTTMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL11280402 | 0.75 | HTT (0.61) | AGTR1HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL11279295 | 0.72 | HTT (0.71) | HTTMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL3720824 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2POLBKMT2ARAB9AMEN1 | |
| Benzenesulfonamide SCHEMBL28134411 | 0.72 | CA2 (0.54) | MAPTSMN1; SMN2LMNAPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |