Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GRM6 | O15303 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11264101 | 0.98 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL11261390 | 0.82 | NPC1 (0.46) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL6516451 | 0.80 | MAPT (0.47) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL11260560 | 0.78 | MAPT (0.48) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL3321379 | 0.77 | KDM4E (0.56) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| Cyclopropane SCHEMBL11655513 | 0.75 | HPGD (0.49) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL23413048 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL30300589 | 0.73 | KDM4E (0.46) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL1883906 | 0.73 | ALDH1A1 (0.66) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL9031450 | 0.73 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360681-A | ANTILIPOLYTIC OR DIETETIC AGENT, INTERMEDIATE FOR BIOTIN | HOFFMANN-LA ROCHE INC. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4299968-A | CHEMICAL INTERMEDIATES FOR BIOTIN AND BLOOD LIPID LOWERING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1981-11-10 | — | — | US | disclosed |