Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11255070 | 0.99 | RAB9A (0.48) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11264970 | 0.94 | RAB9A (0.44) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11258673 | 0.88 | RAB9A (0.51) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11261919 | 0.82 | RAB9A (0.46) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11254514 | 0.82 | NPC1 (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2CLK1 | |
| SCHEMBL11253920 | 0.78 | NPC1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2CLK1 | |
| SCHEMBL11262709 | 0.77 | NPC1 (0.45) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL4496509 | 0.75 | NPC1 (0.69) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20015956 | 0.74 | DYRK1A (0.62) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11255758 | 0.72 | RAB9A (0.50) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |