Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 16/20 | 0.45 |
| ▸ | RAB9A | P51151 | 16/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253920 | 0.83 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11264134 | 0.77 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11254514 | 0.76 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11255070 | 0.76 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11261919 | 0.73 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11264970 | 0.72 | RAB9A (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9963487 | 0.70 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1PTPN1 | |
| SCHEMBL11255508 | 0.69 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11253925 | 0.68 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9963609 | 0.67 | PTPN1 (0.56) | NPC1RAB9ASMN1; SMN2PTPN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |