Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258833 | 0.99 | DRD2 (0.34) | DRD2DRD3DRD4SMN1; SMN2TP53 | |
| SCHEMBL11272020 | 0.96 | DRD2 (0.33) | DRD2DRD3DRD4SMN1; SMN2TP53 | |
| SCHEMBL11263429 | 0.94 | TP53 (0.32) | SMN1; SMN2TP53MAPTABCB11ADORA3 | |
| SCHEMBL11273749 | 0.94 | TP53 (0.32) | SMN1; SMN2TP53MAPTABCB11ADORA3 | |
| SCHEMBL11273902 | 0.94 | TP53 (0.32) | SMN1; SMN2TP53MAPTABCB11ADORA3 | |
| SCHEMBL11267380 | 0.94 | TP53 (0.32) | SMN1; SMN2TP53MAPTABCB11ADORA3 | |
| SCHEMBL11269492 | 0.94 | TP53 (0.32) | SMN1; SMN2TP53MAPTABCB11ADORA3 | |
| SCHEMBL11264418 | 0.94 | TP53 (0.32) | SMN1; SMN2TP53MAPTABCB11ADORA3 | |
| SCHEMBL11257358 | 0.94 | TP53 (0.32) | SMN1; SMN2TP53MAPTABCB11ADORA3 | |
| Hydrochloric Acid SCHEMBL11261603 | 0.94 | LMNA (0.32) | SMN1; SMN2TP53MAPTABCB11ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |