Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837102 | 0.88 | KMT2A (0.56) | MAPK1VCAM1ALDH1A1POLBNPC1 | |
| SCHEMBL11273772 | 0.83 | MAPK1 (0.56) | MAPK1VCAM1ALDH1A1POLBHCAR3 | |
| SCHEMBL11638553 | 0.83 | MAPK1 (0.49) | MAPK1VCAM1ALDH1A1POLBHCAR3 | |
| SCHEMBL11265626 | 0.83 | MAPK1 (0.49) | MAPK1VCAM1ALDH1A1POLBHCAR3 | |
| SCHEMBL11837520 | 0.83 | MAPK1 (0.49) | MAPK1VCAM1ALDH1A1POLBHCAR3 | |
| SCHEMBL11477470 | 0.83 | MAPK1 (0.49) | MAPK1VCAM1ALDH1A1POLBHCAR3 | |
| SCHEMBL11274251 | 0.83 | VCAM1 (0.52) | MAPK1VCAM1ALDH1A1POLBHCAR3 | |
| SCHEMBL11637318 | 0.80 | MAPK1 (0.46) | MAPK1VCAM1ALDH1A1POLBHCAR3 | |
| SCHEMBL11636071 | 0.80 | MAPK1 (0.53) | MAPK1NPC1MAPTRAB9A | |
| SCHEMBL11708615 | 0.80 | TXNRD1 (0.50) | MAPK1VCAM1ALDH1A1POLBHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31071-E | 6-Aza-3H-1,4-benzodiazepines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4207322-A | 6-Aryl-s-triazolo-(4,3-alpha)-pyrido-(2,3-f)-(1,4)-diazepines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-06-10 | — | — | US | disclosed |
| US-4110455-A | 6-ARYL-S-TRIAZOLO-(4,3-A)-PYRIDO-(2,3-F)-1,4-DIAZEPINES | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1978-08-29 | — | — | US | disclosed |
| US-4012397-A | 2-Benzoyl-3-amino-pyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-03-15 | — | — | US | disclosed |
| US-4008223-A | SPASMOLYTIC, ANTIPHLOGISTIC, TRANQUILIZER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-02-15 | — | — | US | disclosed |
| US-3969361-A | 2-Benzoyl-3-amino-pyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-07-13 | — | — | US | disclosed |