SCHEMBL11264625

SCHEMBL11264625

COC(=O)c1cc(OC)cc(C(C)=O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
ALDH1A1 P00352 5/20 0.50
KDM4E B2RXH2 3/20 0.50
CA12 O43570 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MAPK1 P28482 2/20 0.49
POLB P06746 3/20 0.48
LMNA P02545 2/20 0.48
GAA P10253 2/20 0.48
NFKB1 P19838 1/20 0.48
XDH P47989 1/20 0.48
GFER P55789 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475746 0.92 CA1 (0.61) CA1CA2ALDH1A1KDM4ECA12
SCHEMBL20630743 0.89 LMNA (0.56) ALDH1A1KDM4EMEN1KMT2AL3MBTL1
SCHEMBL4731536 0.89 CA1 (0.60) CA1CA2ALDH1A1KDM4ECA12
Methyl 3,5-Dimethoxybenzoate SCHEMBL204865 0.87 CA1 (0.61) CA1CA2ALDH1A1KDM4ECA12
SCHEMBL863160 0.85 MAPK1 (0.56) ALDH1A1KDM4EMEN1KMT2AL3MBTL1
SCHEMBL56890 0.84 KDM4E (0.55) CA1CA2ALDH1A1KDM4ECA12
SCHEMBL28904089 0.82 KDM4E (0.53) CA1CA2ALDH1A1KDM4ECA12
SCHEMBL1708875 0.82 PARP1 (0.55) CA1CA2ALDH1A1KDM4ECA12
SCHEMBL5226850 0.82 CA1 (0.52) CA1CA2ALDH1A1KDM4ECA12
SCHEMBL5682878 0.82 CA1 (0.52) CA1CA2ALDH1A1KDM4ECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660182-A1 NAV1.7- AND/OR NAV1.8-INHIBITING ARYL PYRIDINE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS Eurofarma Laboratórios S.A. (BR) 2025-12-10 EP disclosed
WO-2024159285-A1 NAV1.7- AND/OR NAV1.8-INHIBITING ARYL PYRIDINE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS EUROFARMA LABORATÓRIOS S.A. (BR) 2024-08-08 WO disclosed
US-20230195003-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-22 US disclosed
US-20230195003-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-22 US disclosed
US-4341906-A ANALGESICS PFIZER INC. (US) 1982-07-27 US disclosed
US-4310669-A TETRALONE PFIZER INC. (US) 1982-01-12 US disclosed
US-4310668-A Intermediates to 1,9-dihydroxyoctahydrophenanthrenes PFIZER INC. (US) 1982-01-12 US disclosed
US-4310529-A ANALGESICS PFIZER INC. (US) 1982-01-12 US disclosed
US-4270005-A ANALGESICS PFIZER INC. (US) 1981-05-26 US disclosed
US-4268523-A ANALGESICS PFIZER INC. (US) 1981-05-19 US disclosed
US-4268692-A ANALGESICS PFIZER INC. (US) 1981-05-19 US disclosed
US-4237133-A ANALGESICS PFIZER INC. (US) 1980-12-02 US disclosed
US-4188495-A 1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor PFIZER INC. (US) 1980-02-12 US disclosed