SCHEMBL20630743

SCHEMBL20630743

COc1cc(C(C)=O)cc(C(C)=O)c1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
MAPK1 P28482 3/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CYP3A4 P08684 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
USP2 O75604 1/20 0.48
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
CA5A P35218 1/20 0.48
ALDH1A1 P00352 3/20 0.48
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
ABCG2 Q9UNQ0 1/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 2/20 0.45
PARP1 P09874 1/20 0.45
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL863160 0.95 MAPK1 (0.56) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL5682878 0.91 CA1 (0.52) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL11264625 0.89 CA1 (0.53) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL12020820 0.87 LMNA (0.48) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL1189940 0.87 CA5A (0.64) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL25061973 0.85 LMNA (0.47) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL1189073 0.85 LMNA (0.47) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL1188363 0.85 LMNA (0.47) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL1765000 0.85 LMNA (0.47) LMNAMAPK1MEN1KMT2AL3MBTL1
SCHEMBL20630209 0.82 KMT2A (0.54) LMNAMAPK1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4311849-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-01-29 EP disclosed
US-20240107872-A1 Metal complexes UDC IRELAND LIMITED (IE) 2024-03-28 US disclosed
US-20240059721-A1 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-22 US disclosed
EP-4311849-A1 METAL COMPLEXES UDC Ireland Limited (IE) 2024-01-31 EP disclosed
CN-117466945-A metal complex UDC爱尔兰有限公司 2024-01-30 CN disclosed
US-20230288824-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-09-14 US disclosed
US-20230288847-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-09-14 US disclosed
US-20230288847-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-09-14 US disclosed
US-20230280668-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-09-07 US disclosed
US-20230266684-A1 IMAGE FORMING UNIT AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-08-24 US disclosed
US-20230266683-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-08-24 US disclosed
US-20230266683-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-08-24 US disclosed
US-20230195003-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-22 US disclosed
US-20230195003-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-22 US disclosed
WO-2022118186-A1 SENOTHERAPEUTIC COMPOUND BIONEXA S.R.L. (IT) 2022-06-09 WO disclosed
WO-2019008537-A9 MEDICAL COMPOUNDS VERA SALUS RICERCA S.R.L. (IT) 2020-02-20 WO disclosed
WO-2019008537-A1 MEDICAL COMPOUNDS VERA SALUS RICERCA S.R.L. (IT) 2019-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059721-A1 Metal complexes MCU, IMMT, SOD1 LMNA 4738/4885MAPK1 4723/4885MEN1 2052/4885
US-20240107872-A1 Metal complexes MCU, IMMT, SOD1 LMNA 4738/4885MAPK1 4723/4885MEN1 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.