Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262022 | 0.90 | KMT2A (0.42) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11270269 | 0.80 | SMN1; SMN2 (0.39) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11264984 | 0.80 | KMT2A (0.39) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11269796 | 0.78 | PPARD (0.36) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11608010 | 0.77 | GSK3A (0.44) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11271902 | 0.75 | ALDH1A1 (0.40) | MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL4549471 | 0.70 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11270305 | 0.70 | MAPT (0.39) | MAPTALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL11266860 | 0.70 | PPARD (0.35) | — | |
| SCHEMBL11273387 | 0.69 | MEN1 (0.38) | MEN1KMT2AALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350701-A | 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |