Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.36 |
| ▸ | PPARA | Q07869 | 10/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278370 | 0.87 | PPARD (0.41) | PPARDPPARAPPARG | |
| SCHEMBL11264984 | 0.85 | KMT2A (0.39) | PPARDPPARAPPARGKDM4ENPC1 | |
| SCHEMBL11267429 | 0.84 | MAPT (0.41) | PPARDPPARAPI4KAPI4K2BPI4K2A | |
| SCHEMBL11270609 | 0.82 | HCAR1 (0.36) | PPARDPPARAPPARGMAPTGRM1 | |
| SCHEMBL11270269 | 0.82 | SMN1; SMN2 (0.39) | PPARDPPARAPPARGKDM4ENPC1 | |
| SCHEMBL11268398 | 0.82 | ALDH1A1 (0.41) | PPARDPPARAPPARGNPC1ALDH1A1 | |
| SCHEMBL11279347 | 0.82 | MAPT (0.47) | PPARDPPARAPPARGNPC1ALDH1A1 | |
| SCHEMBL11278669 | 0.82 | ALDH1A1 (0.42) | PPARDPPARAPPARGKDM4ENPC1 | |
| SCHEMBL11271902 | 0.77 | ALDH1A1 (0.40) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL11269982 | 0.76 | POLB (0.39) | ALDH1A1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350701-A | 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |