Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | ADK | P55263 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575792 | 0.81 | ALOX5 (0.44) | KDM4ECYP3A4 | |
| SCHEMBL19746 | 0.81 | CYP19A1 (0.45) | ADKKDM4ESLC6A3RAB9AMAOA | |
| Methane SCHEMBL27973705 | 0.80 | CYP19A1 (0.44) | ADKKDM4ESLC6A3RAB9AMAOA | |
| SCHEMBL11733122 | 0.80 | CYP19A1 (0.44) | ADKKDM4ESLC6A3RAB9AMAOA | |
| SCHEMBL11049014 | 0.79 | MAOB (0.49) | MAOAMAOB | |
| SCHEMBL2283832 | 0.79 | CYP3A4 (0.49) | GSK3BKDM4ECYP3A4NPC1RAB9A | |
| SCHEMBL2474551 | 0.79 | MAOB (0.49) | GSK3BADKKDM4EMAOAMAOB | |
| SCHEMBL10381296 | 0.79 | POLB (0.42) | KDM4ERAB9AMAOAMAOB | |
| SCHEMBL127705 | 0.78 | MAPT (0.52) | CYP3A4NPC1RAB9AMAOAMAOB | |
| SCHEMBL11245736 | 0.78 | CYP19A1 (0.46) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025161-B1 | 3-METHYLENE FLAVANONES AND 3-METHYLENE CHROMANONES, ANTIMICROBIAL COMPOSITION CONTAINING SAME AND METHOD OF INHIBITING THE GROWTH OF MICROORGANISMS | MILES LABORATORIES, INC. (US) | 1982-06-09 | — | — | EP | disclosed |
| EP-0025161-A1 | 3-Methylene flavanones and 3-methylene chromanones, antimicrobial composition containing same and method of inhibiting the growth of microorganisms | MILES LABORATORIES, INC. (US) | 1981-03-18 | — | — | EP | disclosed |
| US-4241069-A | MICROBIOCIDES | MILES LABORATORIES, INC. (US) | 1980-12-23 | — | — | US | disclosed |