Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270376 | 0.99 | ABCB11 (0.42) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| SCHEMBL11263663 | 0.96 | ABCB11 (0.43) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| SCHEMBL11263429 | 0.91 | TP53 (0.32) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| SCHEMBL11269492 | 0.91 | TP53 (0.32) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| SCHEMBL11267380 | 0.91 | TP53 (0.32) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| SCHEMBL11257358 | 0.91 | TP53 (0.32) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| SCHEMBL11264418 | 0.91 | TP53 (0.32) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| SCHEMBL11273749 | 0.91 | TP53 (0.32) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| SCHEMBL11273902 | 0.91 | TP53 (0.32) | ABCB11ADORA3ARCYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL11255557 | 0.91 | LMNA (0.32) | ABCB11ADORA3ARCYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |