SCHEMBL11264997

SCHEMBL11264997

O=C(C=Cc1ccc(N2CCOCC2)cc1)C=Cc1ccc(N2CCOCC2)cc1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.75
MAPT P10636 9/20 0.68
RAB9A P51151 6/20 0.68
NPC1 O15118 5/20 0.68
L3MBTL1 Q9Y468 3/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
ALDH1A1 P00352 2/20 0.68
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
MAOB P27338 1/20 0.64
LMNA P02545 3/20 0.60
MITF O75030 1/20 0.58
KDM4E B2RXH2 1/20 0.56
ESR1 P03372 1/20 0.53
HPGD P15428 1/20 0.52
APP P05067 1/20 0.52
FGFR1 P11362 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11823556 0.88 MAPT (0.71) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL11823548 0.88 MAPT (0.71) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL2027015 0.87 MAPT (0.65) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL30209640 0.87 MAPT (0.65) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL3802062 0.87 MAPT (0.65) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL11252325 0.86 PTGS2 (1.00) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL18693305 0.85 MAPT (0.68) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL18693307 0.85 MAPT (0.68) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL30863768 0.85 MAPT (0.86) PTGS2MAPTRAB9ANPC1L3MBTL1
SCHEMBL11244951 0.84 PTGS2 (0.96) PTGS2MAPTRAB9ANPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315982-A Styryl pyrazoline compounds, process for production thereof, and electrophoto graphic material comprising said compounds COPYER CO., LTD. (JP) 1982-02-16 US disclosed