Sugi Predict

Sugi Predict / Compounds / SCHEMBL3802062

SCHEMBL3802062

SCHEMBL3802062

CC(=O)/C=C/c1ccc(N2CCOCC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 13/20 0.65
▸ SMN1; SMN2 Q16637 4/20 0.65
▸ NPC1 O15118 3/20 0.65
▸ RAB9A P51151 3/20 0.65
▸ MEN1 O00255 3/20 0.65
▸ ALDH1A1 P00352 3/20 0.65
▸ KMT2A Q03164 3/20 0.65
▸ L3MBTL1 Q9Y468 2/20 0.65
▸ LMNA P02545 3/20 0.61
▸ MAOB P27338 1/20 0.61
▸ KDM4E B2RXH2 1/20 0.57
▸ PTGS2 P35354 1/20 0.57
▸ MITF O75030 1/20 0.55
▸ ESR1 P03372 1/20 0.54
▸ MAPK1 P28482 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ PRKDC P78527 1/20 0.50
▸ APP P05067 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2027015 1.00 MAPT (0.65) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL2028974 0.89 MAPT (0.57) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL2028976 0.89 MAPT (0.57) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL11264997 0.87 PTGS2 (0.75) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL2028825 0.87 PTGS2 (0.75) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL3731492 0.87 PTGS2 (0.75) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL11823556 0.85 MAPT (0.71) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL11823548 0.85 MAPT (0.71) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL2025033 0.85 PTGS2 (0.73) MAPTSMN1; SMN2NPC1RAB9AMEN1
SCHEMBL3742436 0.85 PTGS2 (0.73) MAPTSMN1; SMN2NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 — — EP claimed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 — — US claimed
EP-1534227-B1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KGAA (DE) 2006-12-27 — — EP claimed
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) 2006-11-30 — — US claimed
EP-1433469-B1 Composition for dyeing keratinous fibres HENKEL KGAA (DE) 2006-10-11 — — EP claimed
US-7105032-B2 Agents used for dyeing keratinous fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-09-12 — — US claimed
EP-1434557-B1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KGAA (DE) 2005-11-09 — — EP claimed
US-20050144740-A1 Agents used for dyeing keratinous fibers HENKEL AG & CO. KGAA (DE) 2005-07-07 — — US claimed
CN-113304129-B Application of mono-ketene monocarbonyl curcumin analogue in preparing antioxidant drugs 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） 2022-11-08 — — CN disclosed
WO-2013068592-A1 INHIBITORS OF CYSTATHIONINE BETA SYNTHASE TO REDUCE THE NEUROTOXIC OVERPRODUCTION OF ENDOGENOUS HYDROGEN SULFIDE FONDATION JEROME LEJEUNE (FR) 2013-05-16 — — WO disclosed
US-20100278767-A1 Lightening Agents and/or Dyes that Contain Aldehyde(s) HENKEL AG & CO. KGAA (DE) 2010-11-04 — — US disclosed
US-20090304620-A1 HAIR TREATMENT PRODUCTS COMPRISING POLYMERS HENKEL AG & CO. KGAA (DE) 2009-12-10 — — US disclosed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 — — US disclosed
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) 2006-11-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090304620-A1 HAIR TREATMENT PRODUCTS COMPRISING POLYMERS ASS1, SRM, COL1A1 MAPT 1499/4885SMN1; SMN2 2049/4885NPC1 4811/4885
US-20050144740-A1 Agents used for dyeing keratinous fibers KRT18, TUBB3, DSG1 MAPT 259/4885SMN1; SMN2 4330/4885NPC1 4556/4885
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections KRT18, CUTA, PLOD2 MAPT 821/4885SMN1; SMN2 4081/4885NPC1 3324/4885
US-20100278767-A1 Lightening Agents and/or Dyes that Contain Aldehyde(s) CCR3, CBR3, CCRL2 MAPT 3855/4885SMN1; SMN2 4679/4885NPC1 4286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.