Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | CDK3 | Q00526 | 4/20 | 0.34 |
| ▸ | AURKA | O14965 | 3/20 | 0.34 |
| ▸ | GRK2 | P25098 | 3/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.33 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.33 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262070 | 0.87 | ALDH1A1 (0.35) | ADORA2AKMT2AMEN1MAPTCCNE1 | |
| Hydrochloric Acid SCHEMBL11262649 | 0.86 | ALDH1A1 (0.34) | ADORA2AKMT2AMEN1MAPTCCNE1 | |
| SCHEMBL11257120 | 0.85 | MAPT (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGKMT2A | |
| SCHEMBL11255987 | 0.82 | KMT2A (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL11256036 | 0.82 | KMT2A (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL11257039 | 0.82 | MAPT (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL11259927 | 0.78 | PIK3CG (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL11260982 | 0.78 | ALDH1A1 (0.41) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL11265038 | 0.76 | MAPT (0.41) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL11253932 | 0.74 | MAPT (0.46) | ADORA2AKMT2AMEN1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |