Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | MITF | O75030 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265038 | 0.84 | MAPT (0.41) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11253932 | 0.82 | MAPT (0.46) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11262657 | 0.81 | MAPT (0.46) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11255421 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11262070 | 0.79 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11265035 | 0.78 | PIK3CD (0.35) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11262649 | 0.78 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL4861743 | 0.69 | GAA (0.62) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11268232 | 0.68 | NPC1 (0.53) | ALDH1A1LMNAMAPTKDM4ECASP2 | |
| SCHEMBL11261115 | 0.68 | MAPT (0.51) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |