Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237452 | 0.80 | HTR2C (0.47) | HTR2CTSHRSMN1; SMN2LMNAMAPT | |
| SCHEMBL8680577 | 0.74 | HTR2C (0.40) | HTR2CTSHRMAPTMEN1KMT2A | |
| SCHEMBL8680638 | 0.70 | HTR2C (0.36) | HTR2CTSHRMAPTMEN1KMT2A | |
| SCHEMBL8680367 | 0.69 | HTR2C (0.35) | HTR2CTSHRMAPTMEN1KMT2A | |
| SCHEMBL8680349 | 0.67 | MTNR1A (0.34) | HTR2CTSHRSMN1; SMN2LMNAMAPT | |
| SCHEMBL8684876 | 0.67 | HTT (0.44) | HTR2CTSHRMAPTMEN1KMT2A | |
| SCHEMBL11269716 | 0.67 | HTR2C (0.41) | HTR2CTSHRSMN1; SMN2LMNAMAPT | |
| Prococene I SCHEMBL29794343 | 0.66 | HTR2C (0.58) | HTR2CTSHRSMN1; SMN2LMNAMAPT | |
| Prococene I SCHEMBL118080 | 0.66 | HTR2C (0.58) | HTR2CTSHRSMN1; SMN2LMNAMAPT | |
| SCHEMBL8680192 | 0.66 | TDP1 (0.35) | HTR2CTSHRSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348508-A | 3-Substituted-7-alkoxy-2,2'-Spirobi[2H-1-benzopyrans] | ARMSTRONG WORLD INDUSTRIES, INC. (US) | 1982-09-07 | — | — | US | claimed |
| US-4348508-A | 3-Substituted-7-alkoxy-2,2'-Spirobi[2H-1-benzopyrans] | ARMSTRONG WORLD INDUSTRIES, INC. (US) | 1982-09-07 | — | — | US | disclosed |