Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333313 | 0.88 | HTR2C (0.32) | HTR2C | |
| SCHEMBL11264128 | 0.85 | CA12 (0.33) | MAPTLMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL11259985 | 0.85 | CA12 (0.33) | MAPTLMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL3877465 | 0.77 | CA12 (0.33) | HTR2CMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL6701609 | 0.73 | CYP2C19 (0.35) | HIF1AEPAS1TSHR | |
| SCHEMBL11237452 | 0.72 | HTR2C (0.47) | HTR2CMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL11265037 | 0.67 | HTR2C (0.41) | HTR2CMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL11586220 | 0.66 | HTR2C (0.38) | HTR2CMAPTKDM4EALDH1A1HPGD | |
| Prococene I SCHEMBL29794343 | 0.65 | HTR2C (0.58) | HTR2CMAPTLMNAKDM4EALDH1A1 | |
| Prococene I SCHEMBL118080 | 0.65 | HTR2C (0.58) | HTR2CMAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010740-B1 | SPIRODIPYRANES AND THEIR USE AS COLOUR FORMERS IN COPYING PROCESSES | BASF Aktiengesellschaft (DE) | 1982-04-21 | — | — | EP | disclosed |
| EP-0010740-A1 | Spirodipyranes and their use as colour formers in copying processes | BASF Aktiengesellschaft (DE) | 1980-05-14 | — | — | EP | disclosed |