SCHEMBL11265094

SCHEMBL11265094

[CH2]CCCCCCC(Br)C(Br)CCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.44
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
FAAH O00519 1/20 0.38
GPR84 Q9NQS5 6/20 0.38
OPRM1 P35372 1/20 0.37
FDPS P14324 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7550878 1.00 ZDHHC7 (0.44) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL9584643 0.86 LCK (0.43) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL28355783 0.81 LCK (0.43) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL202016 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL22207210 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL25185975 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL200037 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL22158068 0.80 LMNA (0.42) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL22207475 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL5932008 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0015824-B1 METAL DITHIOPHOSPHATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ADDITIVES FOR LUBRICATING OILS OROGIL (FR) 1982-02-17 EP claimed
US-4288335-A REACTING ESTER WITH PHOSPHORUS SULFIDE, METAL OXIDE OROGIL (FR) 1981-09-08 US claimed
US-4288335-A REACTING ESTER WITH PHOSPHORUS SULFIDE, METAL OXIDE OROGIL (FR) 1981-09-08 US disclosed