SCHEMBL7550878

SCHEMBL7550878

[CH2]CCCCCCCC(Br)C(Br)CCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.44
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
FAAH O00519 1/20 0.38
GPR84 Q9NQS5 6/20 0.38
OPRM1 P35372 1/20 0.37
FDPS P14324 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11265094 1.00 ZDHHC7 (0.44) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL9584643 0.86 LCK (0.43) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL28355783 0.81 LCK (0.43) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL202016 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL22207210 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL25185975 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL200037 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL22158068 0.80 LMNA (0.42) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL22207475 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84
SCHEMBL5932008 0.80 LMNA (0.54) LMNADNM1TSHRTHRBGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020173489-A1 COMPOSITIONS CONTAINING A MIXTURE OF PHOSPHOROUS COMPOUNDS AND ALKYLGLYCEROLS MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTER E.V. (DE) 2002-11-21 US disclosed
EP-0916343-A1 use of alkzl phosphoric acid compounds for the treatment of psoriatic diseases ASTA Medica Aktiengesellschaft (DE) 1999-05-19 EP disclosed
US-5290769-A Applying compositions for skin disorders ASTA PHARMA AKTIENGESELLSCHAFT (DE) 1994-03-01 US disclosed
EP-0248062-B1 MEDICAMENTS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1992-05-06 EP disclosed
EP-0248858-B1 NOVEL PHOSPHO-COMPOUNDS AND MEDICAMENTS CONTAINING THESE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1990-02-28 EP disclosed
EP-0225608-A2 Medicine Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1987-06-16 EP disclosed
EP-0224925-A2 Phosphorous compounds and medicines containing them Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1987-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173489-A1 COMPOSITIONS CONTAINING A MIXTURE OF PHOSPHOROUS COMPOUNDS AND ALKYLGLYCEROLS PHOSPHO1, PLCG2, PPIP5K2 ZDHHC7 822/4885LCK 429/4885PPARD 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.