Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | BCR | P11274 | 2/20 | 0.58 |
| ▸ | CASR | P41180 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936949 | 0.87 | MAOB (0.54) | CASRHDAC4HDAC8DRD2DRD4 | |
| SCHEMBL4090500 | 0.84 | ABL1 (0.59) | ABL1ABCB1BCRCASRHDAC4 | |
| SCHEMBL19496757 | 0.83 | HTR7 (0.59) | ABL1ABCB1BCRCASRHDAC4 | |
| SCHEMBL30516648 | 0.82 | MAOB (0.66) | ABL1ABCB1BCRHDAC4HDAC8 | |
| SCHEMBL6477170 | 0.82 | ABL1 (0.58) | ABL1ABCB1BCRCASRHDAC4 | |
| SCHEMBL3720497 | 0.82 | ABL1 (0.58) | ABL1ABCB1BCRCASRHDAC4 | |
| SCHEMBL1521163 | 0.82 | ABL1 (0.58) | ABL1ABCB1BCRCASRHDAC4 | |
| SCHEMBL10468492 | 0.82 | MAOB (0.66) | ABL1ABCB1BCRHDAC4HDAC8 | |
| SCHEMBL2932096 | 0.81 | CYP4F2 (0.48) | CYP4F2CYP4A11LMNAHPGDTSHR | |
| SCHEMBL30987239 | 0.81 | TRPA1 (0.50) | CYP4F2CYP4A11MAOBTSHRHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342756-A | AS ANTITHROMBOTIC AGENTS AND ANTIASTHMATIC AGENTS | GLAXO GROUP LIMITED (GB) | 1982-08-03 | — | — | US | disclosed |