Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 14/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168503 | 0.93 | SIGMAR1 (0.34) | EPHX1SIGMAR1NAAAHRH4HRH3 | |
| SCHEMBL11155609 | 0.92 | EPHX1 (0.34) | EPHX1SIGMAR1NAAAHRH4HRH3 | |
| SCHEMBL11160453 | 0.91 | EPHX1 (0.35) | EPHX1SIGMAR1NAAAHRH4HRH3 | |
| SCHEMBL11155491 | 0.91 | HDAC6 (0.36) | ESR1 | |
| SCHEMBL11149398 | 0.89 | HDAC6 (0.37) | EPHX1ESR1 | |
| SCHEMBL11264437 | 0.89 | SIGMAR1 (0.33) | EPHX1SIGMAR1NAAAHRH4HRH3 | |
| SCHEMBL11153059 | 0.84 | LMNA (0.43) | ESR1 | |
| SCHEMBL11153209 | 0.82 | LMNA (0.44) | ESR1 | |
| SCHEMBL11172342 | 0.82 | HDAC6 (0.39) | ESR1 | |
| SCHEMBL11155862 | 0.80 | TTR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |
| EP-0024282-A1 | Benzoyl derivatives, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-03-04 | — | — | EP | disclosed |