Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263887 | 0.84 | LMNA (0.42) | BRD4LMNAGAATDP1MEN1 | |
| SCHEMBL11277450 | 0.81 | LMNA (0.40) | BRD4LMNAGAATDP1MEN1 | |
| SCHEMBL11538814 | 0.74 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11535600 | 0.74 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11536712 | 0.74 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11537335 | 0.73 | LMNA (0.50) | LMNAKMT2AALDH1A1POLBNPC1 | |
| SCHEMBL2062273 | 0.72 | LMNA (0.53) | LMNAGAATDP1MEN1KMT2A | |
| SCHEMBL10825856 | 0.71 | CHRM4 (0.49) | BRD4LMNATDP1KMT2AALDH1A1 | |
| SCHEMBL10072498 | 0.70 | CCR1 (0.53) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11538275 | 0.70 | LMNA (0.50) | LMNAGAATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314839-A | 1,2,3-Thiadiazole-5-carboxylic acid amide derivatives, process for making the same and herbicidal growth regulating defoliating and fungicidal compositions containing same | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | claimed |